HPLC

A guide to maintaining your HPLC

LC Services -The choice for the future

Many laboratories today are under increasing pressure to run samples around the clock –365 days per year. Consequently manufacturers have moved to improve the reliability, durability and performance achievable by their chromatographic systems . Many modern chromatographs aim to deliver performance characteristics including fewer repeat injections, stable operation at all temperatures, faster run times and minimal carryover. However to achieve these advances whilst maintaining maximum uptime (less maintenance, fewer repairs) places a greater burden on expert quality of care to achieve these parallel goals.

LC Services Ltd has proven itself consistently capable of providing the same level of comprehensive service support as is provided by many manufacturers for their modern chromatography systems.

Unlike older generation chromatographs optimised operation of modern instruments also requires a thorough knowledge of the software involved with instrument control, data capture, networking and regulatory compliance. Consequently expert support of new generation chromatographs requires multidisciplinary servicing expertise, knowledge of quality and regulatory procedures and immediate access to manufacturer’s spares.

KEY PREVENTATIVE MAINTENANCE PROCEDURES: request full details here

Pumps

1. Check Operation

2. Clean/Check operation of fans

3. Clean/Check circuit, boards/switches/connectors

4. Remove and service pump heads

5. Check motor, drives and cams

6. Replace any parts if deemed necessary and record on Engineers Report

7. Check flow rate at 1ml/min for 5 Mins and record result on Engineers Report

Autosamplers

1. Check Operation

2. Clean/Check operation of fans

3. Clean/Check circuit boards/switches/connectors

4. Remove and Service Injector, Needle, and Sample Delivery assemblies

5. Check all motors and drives

6. Replace any parts if deemed necessary and record on Engineers Report

7. Carry out test injections (Preferably by customer)

Detectors

1. Check Operation

2. Clean/Check operation of fans, circuit boards, switches and connectors

3. Remove and Inspect Flowcell assembly

4. Inspect Lamp, record lamp Hrs on Engineers Report (if applicable)

5. Record lamp reference/sample energy at 238nm on Engineers Report

6. Check all motors and drives

7. Replace any parts if deemed necessary and record on Engineers Report

For more information on qualification of your HPLC click on the link here

For more details on LCMS equipment click here